Subcutaneous Allergen Immunotherapy (SCIT)

This method is used to abate allergies by gradually sensitizing individuals to the allergen. There are two different methods to achieve this: traditional and cluster.

Traditional (Standard) Immunotherapy

Schedule

• 1 shot per visit
• Visits: 1-2× per week
• Build-up phase: 3-6 months
• Maintenance: every 3-4 weeks for 3-5 years

Pros

• Lowest risk of reactions
• Well-studied, used for decades
• Easier on sensitive or high-risk patients

Cons

• Slow - many clinic visits
• Takes months before a strong benefit

Who should choose Traditional

Better choice if you:

• Have uncontrolled asthma
• Have had prior severe reactions to shots
• They are very sensitive to allergens
• Prefer short visits even if it takes longer

Cluster Immunotherapy

Schedule

• 2-3 shots per visit, spaced 30 minutes apart
• Visits: 1-2 days per week
• Build-up phase: 4-8 weeks
• Maintenance: every 3-4 weeks for 3-5 years

Pros

• Reach maintenance 3-5× faster
• Fewer total visits
• Faster symptom relief

Cons

• Slightly higher risk of systemic reactions
• Visits are longer (60-90 minutes)
• Not ideal for people with asthma that’s poorly controlled or a history of severe reactions

Who is a good candidate for Cluster

You’re usually a good fit if you:

• Have moderate–severe allergic rhinitis
• Are healthy with well-controlled asthma
• Can stay in the clinic longer per visit
• Want faster relief and fewer trips

Safety Comparison

Clinics usually require:

• Pre-medication with antihistamines for cluster
• Longer observation time
• Good asthma control