Sjögren syndrome is typically caused by autoantibodies to the lacrimal and salivary glands. This causes dry eyes (xerophthalmia) and dry mouth (xerostomia). As a result, enlarged parotid and lacrimal glands due to chronic inflammation are present in patients. As a result of the dry mouth, cracked lips, foul breath, and

Sensitive Tests * ANA antibody Specific tests * Anti-dsDNA * Anti-SmithAntibodies * Anti-Ro/SSA Antibodies * Anti-La/SSB Antibodies Presentation * Photosensitivity * Malar rash - Butterfly rash on face * Discoid rash - A circular, raised, and scaly skin lesion that typically appears on the face, scalp, or other sun-exposed areas * pleuritis - presence of a friction